Patient-derived xenograft models for oncology drug discovery
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چکیده
منابع مشابه
Patient-derived xenograft models for oncology drug discovery
The success of targeted therapies for cancer patients rests on three major components: the right target(s), the right drug and drug combination, and the right patient population. Although much progress has been made in understanding the mechanism of disease and in refi ning pharmaceutical properties of therapeutic agents, the attrition rates between target discovery and drug marketing approval ...
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leading cause of cancer-related death of North American males.1 The disease is at present incurable once it has metastasized, and most deaths from this disease are due to metastases that are highly resistant to current conventional therapies. Prostate cancer is considered a multifocal disease that generally consists of a dominant cancer and one or more concurrent cancers of smaller volume with ...
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ژورنال
عنوان ژورنال: Journal of Cancer Metastasis and Treatment
سال: 2015
ISSN: 2394-4722
DOI: 10.4103/2394-4722.152769